WebThe open-label, randomized POLLUX trial compared safety and efficacy of lenalidomide and dexamethasone with or without daratumumab in 569 patients with RRMM (median age = … WebIntroduction: Daratumumab (DARA) is a human, CD38-targeting, IgG1κ monoclonal antibody approved as monotherapy in relapsed/refractory multiple myeloma (RRMM) and in combination with standard of care for RRMM and NDMM.The addition of DARA to standard-of-care regimens in phase 3 studies has consistently improved progression-free survival …
DRd vs Rd - Pollux Study - Multiple Myeloma Clinical Trials
WebApr 26, 2024 · Pollux is the brightest star in the constellation Gemini, and the 17th brightest in the entire night sky. However, contrary to convention, Pollux bears the designation Beta Geminorum, which by rights should apply to Castor (Alpha Geminorum), which is the second brightest star in Gemini, and only the 23rd brightest star in the night sky. At a distance of … WebNov 3, 2024 · In the phase 3 POLLUX study in patients with RRMM, adding daratumumab to Rd (D-Rd) more than doubled complete response (CR) or better rates, induced a > … discount orvis luggage
POLLUX Study: Daratumumab Plus Len-Dex in Relapsed Myeloma
WebJun 11, 2015 · The Sun joins Pollux on July 15. Fixed star Pollux, Beta Geminorum, is a 1.14 magnitude giant yellow-orange star, located in the head of the Southern Twin of Gemini Constellation.Even though classified as the beta star of Gemini, it is in fact brighter than its twin Castor (α Geminorum).. On June 16, 2006, it was revealed that the Pollux star has … WebFeb 10, 2024 · Four of these studies involved daratumumab (POLLUX, CASTOR, CANDOR, APOLLO), and two involved isatuximab (ICARIA and IKEMA) as the anti-CD38 monoclonal antibody. It is not surprising, given the single-agent activity of both daratumumab and isatuximab, that all six of these studies have demonstrated … WebDec 19, 2024 · Activities 2024 Hematology Meeting Multiple Myeloma POLLUX Follow-up. Daratumumab + Rd vs Rd Alone in Relapsed/Refractory Myeloma: Extended Follow-up From POLLUX. Slideset Download. Conference Coverage. four vessel arch